World Kidney Day

World Kidney Day is a global awareness campaign aiming at informing the public on kidneyhealth issues. More specifically, this year World Kidney Day is celebrated on March 9,andthe theme for the 2017 World Kidney Day campaign isobesity with focus on informing the medical community and the public about the harmful effects of obesity in relation to kidney disease.

According to World Health Organisation (WHO), "obesity" is defined as abnormal or excessive accumulation of body fat that may impair health.It is estimated that in 2014 more than 1.9 billion adults were overweight, with obese exceeding 600 million. More generally, obesity is prevalence in women of any age is higher than in men globally, with 21% of women and 18% men to be obese by 2025.

Obesity is a potent risk factor for the development of nephrolithiasis and kidney cancer, it increases the risk of developing major risk factors of Chronic Kidney Disease (CKD), like diabetes and hypertension, and it has a direct impact on the development of CKD and end stage renal disease (ESRD). People who are overweight or obese have 2 to 7 more chances of developing ESRD compared to those of normal weight. In individuals affected by obesity, the kidneys filter more blood than normal (hyperfiltration) to meet the metabolic demands of the increased body weight. The hyperfiltration is a maladaptive response in the long termthat can drive to glomerulosclerosisand a CKD development.

This year's campaign highlights the fact that reducing obesity may reverse or slow the progression of CKD and strongly suggests that obesity can largely be avoided by adopting a healthy lifestyle including proper diet and physical activity, significantly contributing to the prevention of obesity and renal disease.

Fotis Makris, Scientific Director at Mesogeios Dialysis Center in Palaio Faliro 

Bibliography

Michael E Hall, Jussara M do Carmo, Alexandre A da Silva, Luis A Juncos, Zhen Wang, John E Hal:Obesity, hypertension, and chronic kidney disease. International Journal of Nephrology and Renovascular Disease, 7:75-88, 2014

Csaba P. Kovesdy, Susan L. Furth, Carmine Zoccali for the World Kidney Day Steering Committee: Obesity and kidney disease: hidden consequences of the epidemic. Kidney International 91: 260-262, 2017

World Health Organization: Obesity and overweight, Fact sheet, Updated June 2016

The Lancet: http://press.thelancet.com/BMI.pdf

Sharon Stall and Joseph A. Vassalotti, M: Obesity & Kidney Disease, http://www.obesityaction.org/

Chi-yuan Hsu, Charles E. McCulloch, Carlos Iribarren, Jeanne Darbinian: Body Mass Index and Risk for End-Stage Renal Disease. Annals of Internal Medicine. 2006 

Jaber, Bertrand L: Current Opinion in Nephrology & Hypertension . 26(2):105, 2017

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